Mucuna pruriens for Parkinson's disease: Low-cost preparation method, laboratory measures and pharmacokinetics profile
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چکیده
منابع مشابه
Mucuna pruriens for Parkinson's disease: Low-cost preparation method, laboratory measures and pharmacokinetics profile
BACKGROUND Parkinson's disease (PD) is a progressive neurological condition. Levodopa (LD) is the gold standard therapy for PD patients. Most PD patients in low-income areas cannot afford long-term daily Levodopa therapy. The aim of our study was to investigate if Mucuna pruriens (MP), a legume with high LD content that grows in tropical regions worldwide, might be potential alternative for poo...
متن کاملMucuna pruriens in Parkinson disease
OBJECTIVE To investigate whether Mucuna pruriens (MP), a levodopa-containing leguminous plant growing in all tropical areas worldwide, may be used as alternative source of levodopa for indigent individuals with Parkinson disease (PD) who cannot afford long-term therapy with marketed levodopa preparations. METHODS We investigated efficacy and safety of single-dose intake of MP powder from roas...
متن کاملLevodopa in Mucuna pruriens and its degradation
Mucuna pruriens is the best known natural source of L-dopa, the gold standard for treatment of Parkinsonism. M. pruriens varieties are protein rich supplements, and are used as food and fodder worldwide. Here, we report L-dopa contents in seeds of fifty six accessions of four M. pruriens varieties, M. pruriens var. pruriens, M. pruriens var. hirsuta, M. pruriens var. utilis and M. pruriens var....
متن کاملToxicity Assessment of Mucuna Pruriens Linn. Seeds
Plants have been used as medicine for the treatment of diseases for thousands of years. These herbal remedies, although natural, can cause some serious damaging effects on the vital organs of the body due to inadequacy in standardization and safety regulations. Mucuna pruriens Linn. belongs to family Fabaceae and is used traditionally in various ailments. The present study reports the acute sys...
متن کاملNutritional quality and physicochemical properties of Mucuna bean (Mucuna pruriens L.) protein isolates
The potential for mucuna bean protein isolate (MBPI) application as functional ingredient in foods is unknown. In this study nutritional quality and physicochemical properties of MBPI were investigated. Bean samples were processed for L-dopa extraction in distilled water adjusted to pH 3.2 at 60°C for 48hr. MBPI was extracted at pH 9.0 and isoelectrically precipitated at pH 4.5. MBPI from raw a...
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ژورنال
عنوان ژورنال: Journal of the Neurological Sciences
سال: 2016
ISSN: 0022-510X
DOI: 10.1016/j.jns.2016.04.001